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Dual Regulatory Functions of the Thin Filament Revealed by Replacement of the Troponin I Inhibitory Peptide with a Linker

Striated muscles are relaxed under low Ca(2+) concentration conditions due to actions of the thin filament protein troponin. To investigate this regulatory mechanism, an 11-residue segment of cardiac troponin I previously termed the inhibitory peptide region was studied by mutagenesis. Several mutan...

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Sonraí Bibleagrafaíochta
Main Authors: Kozaili, Julie Mouannes, Leek, Daniel, Tobacman, Larry S.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2992237/
https://ncbi.nlm.nih.gov/pubmed/20889978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.165753
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