Parathyroid Hormone Activation of Matrix Metalloproteinase-13 Transcription Requires the Histone Acetyltransferase Activity of p300 and PCAF and p300-dependent Acetylation of PCAF

Parathyroid hormone (PTH) regulates the transcription of many genes involved in bone remodeling in osteoblasts. One of these genes is matrix metalloproteinase-13 (MMP-13), which is involved in bone remodeling and early stages of endochondral bone formation. We have previously shown that Mmp-13 gene...

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Autores principales: Lee, Minnkyong, Partridge, Nicola C.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Gene Regulation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2992235/
https://ncbi.nlm.nih.gov/pubmed/20870727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.142141
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