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Insight into the Role of Dynamics in the Conformational Switch of the Small GTP-binding Protein Arf1

Activation of the small GTP-binding protein Arf1, a major regulator of cellular traffic, follows an ordered sequence of structural events, which have been pictured by crystallographic snapshots. Combined with biochemical analysis, these data lead to a model of Arf1 activation, in which opening of it...

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Main Authors: Buosi, Vanessa, Placial, Jean-Pierre, Leroy, Jean-Louis, Cherfils, Jacqueline, Guittet, Éric, van Heijenoort, Carine
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2992232/
https://ncbi.nlm.nih.gov/pubmed/20861011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.134445
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