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Supercoiling of the DNA template during transcription.

Transcription of a right-handed double-helical DNA requires a relative rotation of the RNA polymerase and its nascent RNA around the DNA. We describe conditions under which the resistance to the rotational motion of the transcription ensemble around the DNA can be large. In such cases, the advancing...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Liu, L F, Wang, J C
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1987
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299221/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2823250/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.20.7024
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