Structural and pathological effects of synthesis of hepatitis B virus large envelope polypeptide in transgenic mice.

Overproduction of the hepatitis B virus (HBV) large envelope polypeptide by transgenic mice containing the entire HBV envelope coding region leads to the formation of extremely long (up to 800 nm), occasionally branching, filamentous 22-nm-diameter hepatitis B surface antigen particles that accumula...

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Detalhes bibliográficos
Main Authors: Chisari, F V, Filippi, P, Buras, J, McLachlan, A, Popper, H, Pinkert, C A, Palmiter, R D, Brinster, R L
Formato: Artigo
Idioma:Inglês
Publicado em: 1987
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC299194/
https://ncbi.nlm.nih.gov/pubmed/3477814
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