Recovery from ultraviolet light-induced inhibition of DNA synthesis requires umuDC gene products in recA718 mutant strains but not in recA+ strains of Escherichia coli.

Ultraviolet light (UV) inhibits DNA replication in Eschericia coli and induces the SOS response, a set of survival-enhancing phenotypes due to derepression of DNA damage-inducible genes, including recA and umuDC. Recovery of DNA synthesis after UV irradiation ("induced replisome reactivation," or IR...

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Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Principais autores:	Witkin, E M, Roegner-Maniscalco, V, Sweasy, J B, McCall, J O
Formato:	Artigo
Idioma:	Inglês
Publicado:	National Academy of Sciences 1987
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299173/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3309946/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.19.6805
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