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Non-Viral Gene Transfer as a Tool for Studying Transcription Regulation of Xenobiotic Metabolizing Enzymes

Numerous xenobiotic metabolizing enzymes are regulated by nuclear receptors at transcriptional level. The challenge we currently face is to understand how a given nuclear receptor interacts with its xenobiotics, migrates into nucleus, binds to the xenobiotic response element of a target gene, and re...

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Detalhes bibliográficos
Main Authors: Bonamassa, Barbara, Liu, Dexi
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2991602/
https://ncbi.nlm.nih.gov/pubmed/20713102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.addr.2010.08.005
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