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Identification of Amyloid Plaques in Retinas from Alzheimer’s Patients and Noninvasive In Vivo Optical Imaging of Retinal Plaques in a Mouse Model

Noninvasive monitoring of β-amyloid (Aβ) plaques, the neuropathological hallmarks of Alzheimer's disease (AD), is critical for AD diagnosis and prognosis. Current visualization of Aβ plaques in brains of live patients and animal models is limited in specificity and resolution. The retina as an...

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Detalhes bibliográficos
Main Authors: Koronyo-Hamaoui, Maya, Koronyo, Yosef, Ljubimov, Alexander V., Miller, Carol A., Ko, MinHee K., Black, Keith L., Schwartz, Michal, Farkas, Daniel L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2991559/
https://ncbi.nlm.nih.gov/pubmed/20550967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroimage.2010.06.020
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