An Improved Method for Enhanced Production and Biological Activity of Human Secretory Leukocyte Protease Inhibitor (SLPI) in Pichia pastoris

The human secretory leukocyte protease inhibitor (SLPI) is an 11.7 kD cysteine-rich protein that has been shown to possess anti-protease, anti-inflammatory, and antimicrobial properties. By using a Pichia pastoris strain that overproduces protein disulfide isomerase (PDI), we obtained greater than f...

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Main Authors: Li, Zhiguo, Moy, Allison, Gomez, Seth R., Franz, Andreas H., Lin-Cereghino, Joan, Lin-Cereghino, Geoff P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2991533/
https://ncbi.nlm.nih.gov/pubmed/20971072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2010.10.067
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