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Agonist-induced internalization of kappa-opioid receptors in noradrenergic neurons of the rat locus coeruleus

Kappa opioid receptors (κOR) are positioned to modulate pre- and post-synaptic responses of norepinephrine-containing neurons in the rat locus coeruleus (LC). The ability of an acute systemic injection of a long acting κOR agonist, U50,488, to induce trafficking of κOR was assessed in the LC using i...

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Detalhes bibliográficos
Main Authors: Reyes, B. A. S., Chavkin, Charles, Van Bockstaele, E. J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2991477/
https://ncbi.nlm.nih.gov/pubmed/20884346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchemneu.2010.09.003
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