STAT5 IS CRITICAL TO MAINTAIN EFFECTOR CD8+ T CELL RESPONSES

During an immune response, most effector T cells die, while some are maintained and become memory T cells. Factors controlling the survival of effector CD4+ and CD8+ T cells remain unclear. Here, we assessed the role of IL-7, IL-15, and their common signal transducer, STAT5, in maintaining effector...

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Hlavní autoři: Tripathi, Pulak, Kurtulus, Sema, Wojciechowski, Sara, Sholl, Allyson, Hoebe, Kasper, Morris, Suzanne C., Finkelman, Fred D., Grimes, H. Leighton, Hildeman, David A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2991082/
https://ncbi.nlm.nih.gov/pubmed/20644163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000842
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