CXC chemokine receptor 4 expressed in T cells plays an important role in the development of collagen-induced arthritis

INTRODUCTION: Chemokines and their receptors are potential therapeutic targets in rheumatoid arthritis (RA). Among these, several studies suggested the involvement of CXC chemokine 4 (CXCR4) and its ligand CXC ligand 12 (SDF-1) in RA pathogenesis. However, the role of these molecules in T-cell funct...

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Main Authors: Chung, Soo-Hyun, Seki, Keisuke, Choi, Byung-Il, Kimura, Keiko B, Ito, Akihiko, Fujikado, Noriyuki, Saijo, Shinobu, Iwakura, Yoichiro
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2991023/
https://ncbi.nlm.nih.gov/pubmed/20939892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3158
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