TPH2 5′- and 3′-Regulatory Polymorphisms Are Differentially Associated with HPA Axis Function and Self-Injurious Behavior in Rhesus Monkeys

Tryptophan hydroxylase-2 (TPH2) synthesizes neuronal serotonin and is linked to numerous behavioral traits. We have previously characterized the functionality of polymorphisms (especially 2051A>C) in 3′-UTR of rhesus monkey TPH2 (rhTPH2). This study further assessed the functionality of additiona...

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Bibliographic Details
Main Authors: Chen, Guo-Lin, Novak, Melinda A., Meyer, Jerrold S., Kelly, Brian J., Vallender, Eric J., Miller, Gregory M.
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2990963/
https://ncbi.nlm.nih.gov/pubmed/20059554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1601-183X.2010.00564.x
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