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Regulatory BC1 RNA and the Fragile X Mental Retardation Protein: Convergent Functionality in Brain

BACKGROUND: BC RNAs and the fragile X mental retardation protein (FMRP) are translational repressors that have been implicated in the control of local protein synthesis at the synapse. Work with BC1 and Fmr1 animal models has revealed that phenotypical consequences resulting from the absence of eith...

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Autori principali: Zhong, Jun, Chuang, Shih-Chieh, Bianchi, Riccardo, Zhao, Wangfa, Paul, Geet, Thakkar, Punam, Liu, David, Fenton, André A., Wong, Robert K. S., Tiedge, Henri
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2990754/
https://ncbi.nlm.nih.gov/pubmed/21124905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015509
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