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A novel TRH analog, Glp–Asn–Pro–D-Tyr–D-TrpNH(2), binds to [(3)H][3-Me-His(2)]TRH-labelled sites in rat hippocampus and cortex but not pituitary or heterologous cells expressing TRHR1 or TRHR2
Glp–Asn–Pro–D-Tyr–D-TrpNH(2) is a novel synthetic peptide that mimics and amplifies central actions of thyrotropin-releasing hormone (TRH) in rat without releasing TSH. The aim of this study was to compare the binding properties of this pentapeptide and its all-L counterpart (Glp–Asn–Pro–Tyr–TrpNH(2...
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| Principais autores: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2990697/ https://ncbi.nlm.nih.gov/pubmed/18069127 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2007.11.013 |
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