KRAS mutation detection and prognostic potential in sporadic colorectal cancer using high-resolution melting analysis

BACKGROUND: The development of targeted therapies has created a pressing clinical need for molecular characterisation of cancers. In this retrospective study, high-resolution melting analysis (HRMA) was validated and implemented for screening of 164 colorectal cancer (CRC) patients to detect KRAS ho...

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Autori principali: Deschoolmeester, V, Boeckx, C, Baay, M, Weyler, J, Wuyts, W, Van Marck, E, Peeters, M, Lardon, F, Vermorken, J B
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2010
Soggetti:
Molecular Diagnostics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2990591/
https://ncbi.nlm.nih.gov/pubmed/20959826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605959
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