POD Nanoparticles Expressing GDNF Provide Structural and Functional Rescue of Light-induced Retinal Degeneration in an Adult Mouse

Peptide for ocular delivery (POD) is a novel cationic cell-penetrating peptide (CPP) which, when conjugated with polyethylene glycol (PEG-POD), can deliver plasmid DNA to the retinal pigment epithelium (RPE) of adult murine retina. PEG-POD nanoparticles containing an expression cassette for glial ce...

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Detalhes bibliográficos
Main Authors: Read, Sarah P, Cashman, Siobhan M, Kumar-Singh, Rajendra
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2990513/
https://ncbi.nlm.nih.gov/pubmed/20700110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.167
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