Premature Centromere Division of Metaphase Chromosomes in Peripheral Blood Lymphocytes of Alzheimer's Disease Patients: Relation to Gender and Age

Chromosomal alterations are a feature of both aging and Alzheimer's disease (AD). This study examined if premature centromere division (PCD), a chromosomal instability indicator increased in AD, is correlated with aging or, instead, represents a de novo chromosomal alteration due to acceleratin...

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Detalhes bibliográficos
Main Authors: Živković, Lada, Spremo-Potparević, Biljana, Plećaš-Solarović, Bosiljka, Djelić, Ninoslav, Ocić, Gordana, Smiljković, Predrag, Siedlak, Sandra L., Smith, Mark A., Bajić, Vladan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Journal of Gerontology: BIOLOGICAL SCIENCES
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2990265/
https://ncbi.nlm.nih.gov/pubmed/20805239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glq148
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