A Phase III, Randomized, Non-Inferiority Trial to Assess the Efficacy and Safety of Dihydroartemisinin-Piperaquine in Comparison with Artesunate-Mefloquine in Patients with Uncomplicated Plasmodium falciparum Malaria in Southern Laos

We conducted an open, randomized clinical trial of oral dihydroartemisinin-piperaquine (DP) versus artesunate-mefloquine (AM) in 300 patients in Laos with uncomplicated Plasmodium falciparum malaria as part of a multicentre study in Asia. Survival analysis and adjustment for re-infection showed that...

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Autors principals: Mayxay, Mayfong, Keomany, Sommay, Khanthavong, Maniphone, Souvannasing, Phoutthalavanh, Stepniewska, Kasia, Khomthilath, Tiengthong, Keola, Siamphay, Pongvongsa, Tiengkham, Phompida, Samlane, Ubben, David, Valecha, Neena, White, Nicholas J., Newton, Paul N.
Format: Artigo
Idioma:Inglês
Publicat: The American Society of Tropical Medicine and Hygiene 2010
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2990035/
https://ncbi.nlm.nih.gov/pubmed/21118925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4269/ajtmh.2010.10-0276
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