Evaluation of affinity-based genome-wide DNA methylation data: Effects of CpG density, amplification bias, and copy number variation

DNA methylation is an essential epigenetic modification that plays a key role associated with the regulation of gene expression during differentiation, but in disease states such as cancer, the DNA methylation landscape is often deregulated. There are now numerous technologies available to interroga...

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Autors principals: Robinson, Mark D., Stirzaker, Clare, Statham, Aaron L., Coolen, Marcel W., Song, Jenny Z., Nair, Shalima S., Strbenac, Dario, Speed, Terence P., Clark, Susan J.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2010
Matèries:
Method
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2989998/
https://ncbi.nlm.nih.gov/pubmed/21045081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.110601.110
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