The endogenous soluble VEGF receptor-2 isoform suppresses lymph node metastasis in a mouse immunocompetent mammary cancer model

BACKGROUND: Cancer metastasis contributes significantly to cancer mortality and is facilitated by lymphangiogenesis and angiogenesis. A new splicing variant, endogenous soluble vascular endothelial growth factor receptor-2 (esVEGFR-2) that we recently identified is an endogenous selective inhibitor...

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Detalhes bibliográficos
Main Authors: Shibata, Masa-Aki, Ambati, Jayakrishna, Shibata, Eiko, Albuquerque, Romulo JC, Morimoto, Junji, Ito, Yuko, Otsuki, Yoshinori
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2989928/
https://ncbi.nlm.nih.gov/pubmed/21047425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7015-8-69
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