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Epithelial reticulon 4B (Nogo-B) is an endogenous regulator of Th2-driven lung inflammation

Nogo-B is a member of the reticulon family of proteins (RTN-4B) that is highly expressed in lung tissue; however, its function remains unknown. We show that mice with Th2-driven lung inflammation results in a loss of Nogo expression in airway epithelium and smooth muscle compared with nonallergic mi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wright, Paulette L., Yu, Jun, Di, Y.P. Peter, Homer, Robert J., Chupp, Geoffrey, Elias, Jack A., Cohn, Lauren, Sessa, William C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2989775/
https://ncbi.nlm.nih.gov/pubmed/20975041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20100786
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