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Lack of the purinergic receptor P2X(7) results in resistance to contact hypersensitivity

Sensitization to contact allergens requires activation of the innate immune system by endogenous danger signals. However, the mechanisms through which contact allergens activate innate signaling pathways are incompletely understood. In this study, we demonstrate that mice lacking the adenosine triph...

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Autors principals: Weber, Felix C., Esser, Philipp R., Müller, Tobias, Ganesan, Jayanthi, Pellegatti, Patrizia, Simon, Markus M., Zeiser, Robert, Idzko, Marco, Jakob, Thilo, Martin, Stefan F.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2989767/
https://ncbi.nlm.nih.gov/pubmed/21059855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20092489
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