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Lack of the purinergic receptor P2X(7) results in resistance to contact hypersensitivity

Sensitization to contact allergens requires activation of the innate immune system by endogenous danger signals. However, the mechanisms through which contact allergens activate innate signaling pathways are incompletely understood. In this study, we demonstrate that mice lacking the adenosine triph...

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Detalhes bibliográficos
Main Authors: Weber, Felix C., Esser, Philipp R., Müller, Tobias, Ganesan, Jayanthi, Pellegatti, Patrizia, Simon, Markus M., Zeiser, Robert, Idzko, Marco, Jakob, Thilo, Martin, Stefan F.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2989767/
https://ncbi.nlm.nih.gov/pubmed/21059855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20092489
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