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Cytomegalovirus immunoevasin reveals the physiological role of “missing self” recognition in natural killer cell dependent virus control in vivo

Cytomegaloviruses (CMVs) are renowned for interfering with the immune system of their hosts. To sidestep antigen presentation and destruction by CD8(+) T cells, these viruses reduce expression of major histocompatibility complex class I (MHC I) molecules. However, this process sensitizes the virus-i...

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Bibliografiske detaljer
Main Authors: Babić, Marina, Pyzik, Michal, Zafirova, Biljana, Mitrović, Maja, Butorac, Višnja, Lanier, Lewis L., Krmpotić, Astrid, Vidal, Silvia M., Jonjić, Stipan
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2989764/
https://ncbi.nlm.nih.gov/pubmed/21078887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20100921
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