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Coclustering of CD4 (L3T4) molecule with the T-cell receptor is induced by specific direct interaction of helper T cells and antigen-presenting cells.

Blocking studies with monoclonal antibodies have suggested that helper T cell recognition and triggering involve the CD4 (L3T4) accessory molecule as well as the T-cell receptor (TCR) that is linked to the T3 complex. We have investigated the surface distribution of L3T4 and TCR during the direct in...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Kupfer, A, Singer, S J, Janeway, C A, Swain, S L
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1987
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298968/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2956608/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.16.5888
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