In vitro and In vivo Release of Nerve Growth Factor from Biodegradable Poly-Lactic-Co-Glycolic-Acid Microspheres

Regeneration of peripheral nerves after injury is suboptimal. We now report the long term delivery of nerve growth factor (NGF) by biodegradable poly-lactic-co-glycolic acid (PLGA) microspheres in vitro and in vivo. Lactic to glycolic acid ratios of 50:50 and 85:15 were fabricated using the double e...

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Hlavní autoři: de Boer, Ralph, Knight, Andrew M., Spinner, Robert J., Malessy, Martijn J.A., Yaszemski, Michael J., Windebank, Anthony J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2989534/
https://ncbi.nlm.nih.gov/pubmed/20878933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbm.a.32900
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