Novel application of Ki67 to quantify antigen-specific in vitro lymphoproliferation

Antigen-specific proliferation is a critical function of memory T cells that is often utilised to measure vaccine immunogenicity and T cell function. We proposed that measurement of intracellular expression of the nuclear protein, Ki67, could reliably assess specific T cell proliferation in vitro. K...

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Detalhes bibliográficos
Main Authors: Soares, Andreia, Govender, Lerisa, Hughes, Jane, Mavakla, Wendy, de Kock, Marwou, Barnard, Charlene, Pienaar, Bernadette, Janse van Rensburg, Esme, Jacobs, Gail, Khomba, Gloria, Stone, Lynnette, Abel, Brian, Scriba, Thomas J., Hanekom, Willem A.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2010
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2989440/
https://ncbi.nlm.nih.gov/pubmed/20800066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2010.08.007
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