Type-1 Polarized Dendritic Cells Loaded with Apoptotic Prostate Cancer Cells Are Potent Inducers of CD8(+) T cells against Prostate Cancer Cells and Defined Prostate Cancer-Specific Epitopes

BACKGROUND: In order to develop improved vaccines for patients with recurrent prostate cancer (PCa), we tested the feasibility of using type-1-polarized dendritic cells (DC1s) to cross-present antigens from allogeneic PCa cells and to induce functional CD8(+) T cell responses against PCa cells and a...

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Bibliografiske detaljer
Main Authors: Wieckowski, Eva, Chatta, Gurkamal S., Mailliard, Robbie M., Gooding, William, Palucka, Karolina, Banchereau, Jacques, Kalinski, Pawel
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2989344/
https://ncbi.nlm.nih.gov/pubmed/20717900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.21228
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