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IgG1 Is Pathogenic in Leishmania mexicana Infection

There are over 2 million new cases of leishmaniasis annually, and no effective vaccine has been developed to prevent infection. In murine infection, Leishmania mexicana, which lives intracellularly in host macrophages, has developed pathways to hijack host IgG to induce a suppressive IL-10 response...

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Detalhes bibliográficos
Main Authors: Chu, Niansheng, Thomas, Bolaji N., Patel, Supriya R., Buxbaum, Laurence U.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2989177/
https://ncbi.nlm.nih.gov/pubmed/21037092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1002484
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