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Pregnenolone and ganaxolone reduce operant ethanol self-administration in alcohol-preferring P rats
BACKGROUND: Neuroactive steroids modulate ethanol intake in several self-administration models with variable effects. The purpose of this work was to examine the effects of the long-acting synthetic GABAergic neurosteroid ganaxalone and the endogenous neurosteroid pregnenolone, a precursor of all GA...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2988984/ https://ncbi.nlm.nih.gov/pubmed/20946297 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1530-0277.2010.01300.x |
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