DIFFERENTIAL KINETICS OF α-[(11)C]METHYL-L-TRYPTOPHAN ON PET IN LOW-GRADE BRAIN TUMORS

Increased tryptophan metabolism via the kynurenine pathway is a major mechanism of tumor immuno-resistance. α-[(11)C]Methyl-L-tryptophan (AMT) is a positron emission tomography (PET) tracer for tryptophan catabolism, and increased AMT uptake has been demonstrated in brain tumors. In this study we ev...

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Main Authors: Juhász, Csaba, Muzik, Otto, Chugani, Diane C., Chugani, Harry T., Sood, Sandeep, Chakraborty, Pulak K., Barger, Geoffrey R., Mittal, Sandeep
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2988869/
https://ncbi.nlm.nih.gov/pubmed/20676727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-010-0327-1
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