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Conserved Proximal Promoter Elements Control Repulsive Guidance Molecule c/Hemojuvelin Gene Transcription in Skeletal Muscle
Repulsive guidance molecule c (RGMc) plays a critical role in iron metabolism. Inactivating mutations cause juvenile hemochromatosis, a severe iron overload disorder. Understanding mechanisms controlling RGMc biosynthesis has been hampered by minimal information about the RGMc gene. Here we define t...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2988867/ https://ncbi.nlm.nih.gov/pubmed/20858542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygeno.2010.09.001 |
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