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Microfluidic force spectroscopy for characterization of biomolecular interactions with piconewton resolution
In this paper we present a scalable method based on the use of microfluidics and shear force spectroscopy which can be used for determining the affinity between molecules. Our method involves the use of functionalization of the surface of microfluidic channels with ligand molecules, and the surface...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Institute of Physics
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2988830/ https://ncbi.nlm.nih.gov/pubmed/21103190 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.3491547 |
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