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An Essential Role of the Cytoplasmic Tail of CXCR4 in G-Protein Signaling and Organogenesis

CXCR4 regulates cell proliferation, enhances cell survival and induces chemotaxis, yet molecular mechanisms underlying its signaling remain elusive. Like all other G-protein coupled receptors (GPCRs), CXCR4 delivers signals through G-protein-dependent and -independent pathways, the latter involving...

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Detalhes bibliográficos
Main Authors: Cronshaw, Darran G., Nie, Yuchun, Waite, Janelle, Zou, Yong-Rui
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2988825/
https://ncbi.nlm.nih.gov/pubmed/21124917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015397
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