Radio-induced malignancies after breast cancer postoperative radiotherapy in patients with Li-Fraumeni syndrome

BACKGROUND: There are no specific recommendations for the management of breast cancer patients with germ-line p53 mutations, an exceptional genetic condition, particularly regarding postoperative radiotherapy. Preclinical data suggested that p53 mutations conferred enhanced radiosensitivity in vitro...

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Detalhes bibliográficos
Main Authors: Heymann, Steve, Delaloge, Suzette, Rahal, Arslane, Caron, Olivier, Frebourg, Thierry, Barreau, Lise, Pachet, Corinne, Mathieu, Marie-Christine, Marsiglia, Hugo, Bourgier, Céline
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2988810/
https://ncbi.nlm.nih.gov/pubmed/21059199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1748-717X-5-104
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