Spiral ligament fibrocyte-derived MCP-1/CCL2 contributes to inner ear inflammation secondary to nontypeable H. influenzae-induced otitis media

BACKGROUND: Otitis media (OM), one of the most common pediatric infectious diseases, causes inner ear inflammation resulting in vertigo and sensorineural hearing loss. Previously, we showed that spiral ligament fibrocytes (SLFs) recognize OM pathogens and up-regulate chemokines. Here, we aim to dete...

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Main Authors: Woo, Jeong-Im, Pan, Huiqi, Oh, Sejo, Lim, David J, Moon, Sung K
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2010
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2988798/
https://ncbi.nlm.nih.gov/pubmed/21029462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2334-10-314
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