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Quantitative expression of osteopontin in nasal mucosa of patients with allergic rhinitis: effects of pollen exposure and nasal glucocorticoid treatment

BACKGROUND: Osteopontin (OPN) is a multifunctional cytokine that has been primarily investigated in Th1 diseases. Recently, it has also been implicated in Th2-mediated allergic diseases, such as asthma. The expression of OPN in allergic rhinitis (AR) is currently unknown, as is the effect of intrana...

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Autors principals: O'Neil, Serena E, Malmhäll, Carina, Samitas, Konstantinos, Pullerits, Teet, Bossios, Apostolos, Lötvall, Jan
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2988772/
https://ncbi.nlm.nih.gov/pubmed/21044308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1710-1492-6-28
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