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An estimate of amyotrophic lateral sclerosis heritability using twin data

BACKGROUND: Causative gene mutations have been identified in about 2% of those with amyotrophic lateral sclerosis (ALS), often, but not always, when there is a strong family history. There is an assumption that there is a genetic component to all ALS, but genome-wide association studies have yet to...

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Autores principales: Al-Chalabi, A, Fang, F, Hanby, M F, Leigh, P N, Shaw, C E, Ye, W, Rijsdijk, F
Formato: Artigo
Lenguaje:Inglês
Publicado: BMJ Group 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2988617/
https://ncbi.nlm.nih.gov/pubmed/20861059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jnnp.2010.207464
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