HRAS1-selected chromosome transfer generates markers that colocalize aniridia- and genitourinary dysplasia-associated translocation breakpoints and the Wilms tumor gene within band 11p13.

We show that chromosome-mediated gene transfer can provide an enriched source of DNA markers for predetermined, subchromosomal regions of the human genome. Forty-four human DNA recombinants isolated from a HRAS1-selected chromosome-mediated gene transformant map exclusively to chromosome 11, with se...

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Detalhes bibliográficos
Main Authors: Porteous, D J, Bickmore, W, Christie, S, Boyd, P A, Cranston, G, Fletcher, J M, Gosden, J R, Rout, D, Seawright, A, Simola, K O
Formato: Artigo
Idioma:Inglês
Publicado em: 1987
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC298854/
https://ncbi.nlm.nih.gov/pubmed/3037545
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