HRAS1-selected chromosome transfer generates markers that colocalize aniridia- and genitourinary dysplasia-associated translocation breakpoints and the Wilms tumor gene within band 11p13.

We show that chromosome-mediated gene transfer can provide an enriched source of DNA markers for predetermined, subchromosomal regions of the human genome. Forty-four human DNA recombinants isolated from a HRAS1-selected chromosome-mediated gene transformant map exclusively to chromosome 11, with se...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Porteous, D J, Bickmore, W, Christie, S, Boyd, P A, Cranston, G, Fletcher, J M, Gosden, J R, Rout, D, Seawright, A, Simola, K O
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1987
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298854/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3037545/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.15.5355
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