Nitric oxide and AMPK cooperatively regulate PGC-1α in skeletal muscle cells

Nitric oxide (NO) induces mitochondrial biogenesis in skeletal muscle cells via upregulation of the peroxisome proliferator-activated receptor-γ coactivator 1α (PGC-1α). Further, we have shown that nitric oxide interacts with the metabolic sensor enzyme, AMPK. Therefore, we tested the hypothesis tha...

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Detalhes bibliográficos
Main Authors: Lira, Vitor A, Brown, Dana L, Lira, Ana K, Kavazis, Andreas N, Soltow, Quinlyn A, Zeanah, Elizabeth H, Criswell, David S
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2010
Assuntos:
Skeletal Muscle and Exercise
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2988518/
https://ncbi.nlm.nih.gov/pubmed/20643772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2010.194035
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