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An analysis of the mutagenicity of 1,2-dibromoethane to Escherichia coli: Influence of DNA repair activities and metabolic pathways

The mutagenicity of 1,2-dibromoethane (EDB) to Escherichia coli was reduced by the UV light-induced excision repair system but unaffected by the loss of a major apurinic/apyrimidinic site repair function. At high doses, 70–90% of the EDB-induced mutations were independent of SOS-mutagenic processing...

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Main Authors: Foster, Patricia L., Wilkinson, Wells G., Miller, Judith K., Sullivan, Amy D., Barnes, Wayne M.
Formato: Artigo
Idioma:Inglês
Publicado: 1988
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2988426/
https://ncbi.nlm.nih.gov/pubmed/3054522
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