Mice lacking C1q or C3 show accelerated rejection of minor H disparate skin grafts and resistance to induction of tolerance

Complement activation is known to have deleterious effects on organ transplantation. On the other hand, the complement system is also known to have an important role in regulating immune responses. The balance between these two opposing effects is critical in the context of transplantation. Here, we...

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Main Authors: Baruah, Paramita, Simpson, Elizabeth, Dumitriu, Ingrid E, Derbyshire, Katy, Coe, David, Addey, Caroline, Dyson, Julian, Chai, Jian-Guo, Cook, Terence, Scott, Diane, Botto, Marina
Formato: Artigo
Idioma:Inglês
Publicado em: WILEY-VCH Verlag 2010
Assuntos:
Innate Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2988415/
https://ncbi.nlm.nih.gov/pubmed/20213737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200940158
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