Suppressor of Cytokine Signaling 3 Inhibits LPS-induced IL-6 Expression in Osteoblasts by Suppressing CCAAT/Enhancer-binding Protein β Activity

Suppressor of cytokine signaling 3 (SOCS3) is an important intracellular protein that inhibits cytokine signaling in numerous cell types and has been implicated in several inflammatory diseases. However, the expression and function of SOCS3 in osteoblasts are not known. In this study, we demonstrate...

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Main Authors: Yan, Chunguang, Cao, Jay, Wu, Min, Zhang, Wei, Jiang, Tao, Yoshimura, Aihiko, Gao, Hongwei
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Immunology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2988329/
https://ncbi.nlm.nih.gov/pubmed/20876575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.132084
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