Nucleophosmin C-terminal Leukemia-associated Domain Interacts with G-rich Quadruplex Forming DNA

Nucleophosmin (NPM1) is a nucleocytoplasmic shuttling phosphoprotein, mainly localized at nucleoli, that plays a key role in ribogenesis, centrosome duplication, and response to stress stimuli. Mutations at the C-terminal domain of NPM1 are the most frequent genetic lesion in acute myeloid leukemia...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Main Authors: Federici, Luca, Arcovito, Alessandro, Scaglione, Giovanni L., Scaloni, Flavio, Lo Sterzo, Carlo, Di Matteo, Adele, Falini, Brunangelo, Giardina, Bruno, Brunori, Maurizio
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2010
Ábhair:
Molecular Biophysics
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2988320/
https://ncbi.nlm.nih.gov/pubmed/20858903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.166736
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla