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Intensive lowering of LDL cholesterol with 80 mg versus 20 mg simvastatin daily in 12 064 survivors of myocardial infarction: a double-blind randomised trial

BACKGROUND: Lowering of LDL cholesterol reduces major vascular events, but whether more intensive therapy safely produces extra benefits is uncertain. We aimed to establish efficacy and safety of more intensive statin treatment in patients at high cardiovascular risk. METHODS: We undertook a double-...

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Detalhes bibliográficos
Autor principal: Study of the Effectiveness of Additional Reductions in Cholesterol and Homocysteine (SEARCH) Collaborative Group
Formato: Artigo
Idioma:Inglês
Publicado em: Lancet Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2988223/
https://ncbi.nlm.nih.gov/pubmed/21067805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0140-6736(10)60310-8
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