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The TRIM-NHL Protein TRIM32 Activates MicroRNAs and Prevents Self-Renewal in Mouse Neural Progenitors

In the mouse neocortex, neural progenitor cells generate both differentiating neurons and daughter cells that maintain progenitor fate. Here, we show that the TRIM-NHL protein TRIM32 regulates protein degradation and microRNA activity to control the balance between those two daughter cell types. In...

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Autors principals: Schwamborn, Jens C., Berezikov, Eugene, Knoblich, Juergen A.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2988196/
https://ncbi.nlm.nih.gov/pubmed/19269368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.12.024
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