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Enhancement of choleragen ADP-ribosyltransferase activities by guanyl nucleotides and a 19-kDa membrane protein.

Choleragen activates adenylate cyclase by catalyzing, in the presence of NAD, the ADP-ribosylation of Gs alpha, the stimulatory guanyl nucleotide-binding protein of the cyclase system. Kahn and Gilman [Kahn, R. A. & Gilman, A. G. (1986) J. Biol. Chem. 261, 7906-7911] identified another guanyl nucleo...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Tsai, S C, Noda, M, Adamik, R, Moss, J, Vaughan, M
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1987
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298809/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3110784/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.15.5139
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