Oligo(alpha-deoxynucleotide)s covalently linked to intercalating agents: differential binding to ribo- and deoxyribopolynucleotides and stability towards nuclease digestion.

An octathymidylate was synthesized with the alpha anomer of thymidine instead of the naturally occurring beta anomer. This oligonucleotide binds to complementary sequences containing beta-nucleosides. Binding to ribose-containing oligomers and polymers is much stronger than binding to deoxyribose-co...

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Bibliografiset tiedot
Päätekijät: Thuong, N T, Asseline, U, Roig, V, Takasugi, M, Hélène, C
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1987
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC298807/
https://ncbi.nlm.nih.gov/pubmed/3474645
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