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Altered synaptic plasticity in the mossy fibre pathway of transgenic mice expressing mutant amyloid precursor protein

Aβ peptides derived from the cleavage of amyloid precursor protein are widely believed to play an important role in the pathophysiology of Alzheimer's disease. A common way to study the impact of these molecules on CNS function is to compare the physiology of transgenic mice that overproduce Aβ...

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Detalhes bibliográficos
Main Authors: Witton, Jonathan, Brown, Jon T, Jones, Matthew W, Randall, Andrew D
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2988062/
https://ncbi.nlm.nih.gov/pubmed/21040543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-6606-3-32
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