Directly-observed therapy (DOT) for the radical 14-day primaquine treatment of Plasmodium vivax malaria on the Thai-Myanmar border

BACKGROUND: Plasmodium vivax has a dormant hepatic stage, called the hypnozoite, which can cause relapse months after the initial attack. For 50 years, primaquine has been used as a hypnozoitocide to radically cure P. vivax infection, but major concerns remain regarding the side-effects of the drug...

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Dades bibliogràfiques
Autors principals: Takeuchi, Rie, Lawpoolsri, Saranath, Imwong, Mallika, Kobayashi, Jun, Kaewkungwal, Jaranit, Pukrittayakamee, Sasithon, Puangsa-art, Supalap, Thanyavanich, Nipon, Maneeboonyang, Wanchai, Day, Nicholas PJ, Singhasivanon, Pratap
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2988041/
https://ncbi.nlm.nih.gov/pubmed/21040545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-9-308
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